| SOFT - TIAFT 1998 | Poster Session 1 | Wednesday October 7, 1998 |
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EFFECTS OF VARIOUS HAIR STRIPPING TREATMENTS ON ANALYTICAL RESULTS Thomas D. Donahue, Kathleen A. Rhode and Dan R. Berkable American Toxicology Institute, Las Vegas, NV, USA |
| Previously analyzed hair specimens were subjected to various hair stripping shampoos marketed locally and on the Internet to "cleanse the hair of drugs". These hair samples were prepared by a mechanical pulverization/aqueous extraction procedure and screened by a Kinetic Interaction of Microparticles in a Solution (KIMS) assay. Presumptive positive samples were washed with a buffered solution which was assayed to determine if successful decontamination had been accomplished. Confirmation was performed using established hair GC/MS extraction and derivatization procedures. Comparison of screening and confirmation values of methamphetamine, opiate and cocaine positive hair samples indicates that use of stripping agents generally reduces the amount of drug detected. The average reduction of drug detected by GC/MS confirmation was as follows: cocaine (BE) 5.45% ± 4.78, codeine 8.30% ± 7.88, and methamphetamine 8.00% ± 7.87%. Stripping agents containing lauryl sulfate showed no significant change in reduction of drug detected over agents not having this surfactant. Samples containing higher levels of drug detected were more sensitive to the drug reduction effects of stripping agents. Although these agents produced some statistically significant reductions in drug detected, no previously determined positive result was changed to negative. |
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